ABSTRACT
Novel technologies allow continuous wireless monitoring systems (CWMS) to measure vital signs and these systems might be favorable compared to intermittent monitoring regarding improving outcomes. However, device safety needs to be validated because uncertain evidence challenges the clinical implementation of CWMS. This review investigates the frequency of device-related adverse events in patients monitored with CWMS in general hospital wards. Systematic literature searches were conducted in PubMed and Embase. We included trials of adult patients in general hospital wards monitored with CWMS. Our primary outcome was the frequency of unanticipated serious adverse device effects (USADEs). Secondary outcomes were adverse device effects (ADEs) and serious adverse device effects (SADE). Data were extracted from eligible studies and descriptive statistics were applied to analyze the data. Seven studies were eligible for inclusion with a total of 1485 patients monitored by CWMS. Of these patients, 54 patients experienced ADEs (3.6%, 95% CI 2.8-4.7%) and no USADEs or SADEs were reported (0%, 95% CI 0-0.31%). The studies of the SensiumVitals® patch, the iThermonitor, and the ViSi Mobile® device reported 28 (9%), 25 (5%), and 1 (3%) ADEs, respectively. No ADEs were reported using the HealthPatch, WARD 24/7 system, or Coviden Alarm Management. Current evidence suggests that CWMS are safe to use but systematic reporting of all adverse device effects is warranted.
ABSTRACT
Chest compressions and ventilation attempts can generate aerosols during resuscitation. It is important to determine whether different materials suitable for the blanketing of cardiac arrest patients can diminish exposure to aerosols. In this study, three volatile organic compounds, ethanol, acetone, and isoprene, commonly found in human breath in moistened air, acted as substitutes for aerosols. Here, we present information on the adsorption of these volatiles to three blanketing materials: polyvinyl chloride, polyethylene, and aluminum coated polyethylene terephthalate. After exposure to the surfaces of these materials the test volatiles were quantified by the proton transfer reaction-time of flight-mass spectrometry. There was a trend towards a potentially higher reduction for acetone (p = 0.071) and isoprene (p = 0.050) on polyethylene, compared to polyvinyl chloride and aluminum coated polyethylene terephthalate during the rise interval. Adsorption capacity did not differ between the foils and was between 67% and 70%. From our studies, we propose that the aluminum-coated polyethylene terephthalate surface of space blankets prove adequate to diminish exposure to volatiles in moistened air, and hence to aerosols.
ABSTRACT
The race to develop safe and effective SARS-COV-2 vaccines has moved with unprecedented speed. There are now multiple promising candidates seeking emergency use authorization from the United States Food and Drug Administration and a host of candidates positioned for approval worldwide. Attention has now turned to allocation, distribution and verification of these vaccines, yet this focus exposes that the underlying infrastructure for global delivery and monitoring is threadbare and unevenly distributed. This presents both a barrier and an opportunity to deploy sustainable infrastructure. Major global stakeholders must convene quickly, collaborate, and collectively invest in global standards, legal models, common vocabularies and interoperable biometric-supported digital health technologies. As the COVID-19 vaccine effort scales, governments, private sector and NGOs have the chance to place lasting resources needed for equitable and effective delivery that can pay dividends into the future. Copyright © 2020. Weintraub R et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Insertion of nasogastric tube is one of the commonest clinical procedures. However, very rarely, the tube can coil on itself to form something called a Lariat loop. This is a knot that can cause the tube to get stuck inside the pharynx and can precipitate emergencies like laryngeal obstruction or esophageal rupture. A brief discussion of a case along with the causes and prevention of this complication has been done.